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A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity
DNA and RNA nucleases play a critical role in a growing number of cellular processes ranging from DNA repair to immune surveillance. Nevertheless, many nucleases have unknown or poorly characterized activities. Elucidating nuclease substrate specificities and co-factors can support a more definitive...
Autores principales: | Sheppard, Emily C., Rogers, Sally, Harmer, Nicholas J., Chahwan, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586798/ https://www.ncbi.nlm.nih.gov/pubmed/31222049 http://dx.doi.org/10.1038/s41598-019-45356-z |
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