Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression

Attachment of lipid tails to oligonucleotides has emerged as a powerful technology in constructing cell membrane-anchorable nucleic acid-based probes. In practice, however, conventional lipid-conjugated oligonucleotides fail to distinguish among different cell membranes. Herein, a phosphorylated lip...

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Detalles Bibliográficos
Autores principales: Jin, Cheng, He, Jiaxuan, Zou, Jianmei, Xuan, Wenjing, Fu, Ting, Wang, Ruowen, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586821/
https://www.ncbi.nlm.nih.gov/pubmed/31221964
http://dx.doi.org/10.1038/s41467-019-10639-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586821/
https://www.ncbi.nlm.nih.gov/pubmed/31221964
http://dx.doi.org/10.1038/s41467-019-10639-6

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