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Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression
Attachment of lipid tails to oligonucleotides has emerged as a powerful technology in constructing cell membrane-anchorable nucleic acid-based probes. In practice, however, conventional lipid-conjugated oligonucleotides fail to distinguish among different cell membranes. Herein, a phosphorylated lip...
Autores principales: | Jin, Cheng, He, Jiaxuan, Zou, Jianmei, Xuan, Wenjing, Fu, Ting, Wang, Ruowen, Tan, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586821/ https://www.ncbi.nlm.nih.gov/pubmed/31221964 http://dx.doi.org/10.1038/s41467-019-10639-6 |
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