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Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes

Plasmodium vivax parasites preferentially invade reticulocyte cells in a multistep process that is still poorly understood. In this study, we used ex vivo invasion assays and population genetic analyses to investigate the involvement of complement receptor 1 (CR1) in P. vivax invasion. First, we obs...

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Detalles Bibliográficos
Autores principales: Prajapati, Surendra Kumar, Borlon, Céline, Rovira-Vallbona, Eduard, Gruszczyk, Jakub, Menant, Sebastien, Tham, Wai-Hong, Kattenberg, Johanna Helena, Villasis, Elizabeth, De Meulenaere, Katlijn, Gamboa, Dionicia, Vinetz, Joseph, Fujita, Ricardo, Xuan, Xa Nguyen, Urbano Ferreira, Marcelo, Niño, Carlos H., Patarroyo, Manuel A., Spanakos, Gregory, Kestens, Luc, Abbeele, Jan Van Den, Rosanas-Urgell, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586822/
https://www.ncbi.nlm.nih.gov/pubmed/31221984
http://dx.doi.org/10.1038/s41598-019-45228-6