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The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans

Chd1 is a chromatin remodeler that is involved in nucleosome positioning and transcription. Deletion of CHD1 is a frequent event in prostate cancer. The Structural Maintenance of Chromosome (SMC) complex cohesin mediates long-range chromatin interactions and is involved in maintaining genome stabili...

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Detalles Bibliográficos
Autores principales: Boginya, Alexandra, Detroja, Rajesh, Matityahu, Avi, Frenkel-Morgenstern, Milana, Onn, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586844/
https://www.ncbi.nlm.nih.gov/pubmed/31222142
http://dx.doi.org/10.1038/s41598-019-45263-3