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Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells

Prostate cancer (PCa) is the most common cancer amongst men. A novel androgen receptor (AR) antagonist, enzalutamide (ENZA) has recently been demonstrated to enhance the effect of radiation (XRT) by impairing the DNA damage repair process. This study aimed to identify a radiosensitive gene signature...

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Detalles Bibliográficos
Autores principales: Ghashghaei, Maryam, Niazi, Tamim M., Aguilar-Mahecha, Adriana, Klein, Kathleen Oros, Greenwood, Celia M. T., Basik, Mark, Muanza, Thierry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586860/
https://www.ncbi.nlm.nih.gov/pubmed/31221986
http://dx.doi.org/10.1038/s41598-019-44991-w