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Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells
Prostate cancer (PCa) is the most common cancer amongst men. A novel androgen receptor (AR) antagonist, enzalutamide (ENZA) has recently been demonstrated to enhance the effect of radiation (XRT) by impairing the DNA damage repair process. This study aimed to identify a radiosensitive gene signature...
Autores principales: | Ghashghaei, Maryam, Niazi, Tamim M., Aguilar-Mahecha, Adriana, Klein, Kathleen Oros, Greenwood, Celia M. T., Basik, Mark, Muanza, Thierry M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586860/ https://www.ncbi.nlm.nih.gov/pubmed/31221986 http://dx.doi.org/10.1038/s41598-019-44991-w |
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