Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework

Cancer cells undergoing epithelial-mesenchymal transition (EMT) acquire stem cell-like phenotype associated with malignant behaviour, chemoresistance, and relapse. Current two-dimensional (2D) in-vitro culture models of tumorigenesis are inadequate to replicate the complexity of in-vivo microenviron...

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Detalles Bibliográficos
Autores principales: Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586872/
https://www.ncbi.nlm.nih.gov/pubmed/31222037
http://dx.doi.org/10.1038/s41598-019-45384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586872/
https://www.ncbi.nlm.nih.gov/pubmed/31222037
http://dx.doi.org/10.1038/s41598-019-45384-9

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