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In-silico Prediction of Synergistic Anti-Cancer Drug Combinations Using Multi-omics Data

Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two or more drugs are applied simultaneously, offers one promising approach to add...

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Detalles Bibliográficos
Autores principales: Celebi, Remzi, Bear Don’t Walk, Oliver, Movva, Rajiv, Alpsoy, Semih, Dumontier, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586895/
https://www.ncbi.nlm.nih.gov/pubmed/31222109
http://dx.doi.org/10.1038/s41598-019-45236-6