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In-silico Prediction of Synergistic Anti-Cancer Drug Combinations Using Multi-omics Data
Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two or more drugs are applied simultaneously, offers one promising approach to add...
Autores principales: | Celebi, Remzi, Bear Don’t Walk, Oliver, Movva, Rajiv, Alpsoy, Semih, Dumontier, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586895/ https://www.ncbi.nlm.nih.gov/pubmed/31222109 http://dx.doi.org/10.1038/s41598-019-45236-6 |
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