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Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells

Despite advances in stem cell research, cell transplantation therapy for liver failure is impeded by a shortage of human primary hepatocytes (HPH), along with current differentiation protocol limitations. Several studies have examined the concept of co-culture of human induced pluripotent cells (hiP...

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Detalles Bibliográficos
Autores principales: Pettinato, Giuseppe, Lehoux, Sylvain, Ramanathan, Rajesh, Salem, Mohamed M., He, Li-Xia, Muse, Oluwatoyosi, Flaumenhaft, Robert, Thompson, Melissa T., Rouse, Emily A., Cummings, Richard D., Wen, Xuejun, Fisher, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586904/
https://www.ncbi.nlm.nih.gov/pubmed/31222080
http://dx.doi.org/10.1038/s41598-019-45514-3