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Localization of RalB signaling at endomembrane compartments and its modulation by autophagy

The monomeric GTPase RalB controls crucial physiological processes, including autophagy and invasion, but it still remains unclear how this multi-functionality is achieved. Previously, we reported that the RalGEF (Guanine nucleotide Exchange Factor) RGL2 binds and activates RalB to promote invasion....

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Detalles Bibliográficos
Autores principales: Singh, Manish Kumar, Martin, Alexandre P. J., Joffre, Carine, Zago, Giulia, Camonis, Jacques, Coppey, Mathieu, Parrini, Maria Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586930/
https://www.ncbi.nlm.nih.gov/pubmed/31222145
http://dx.doi.org/10.1038/s41598-019-45443-1