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Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation

BACKGROUND: Bilirubin, a by-product of haem catabolism, possesses potent endogenous antioxidant and platelet inhibitory properties. These properties may be useful in inhibiting inappropriate platelet activation and ROS production; for example, during storage for transfusion. Given the hydrophobicity...

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Detalles Bibliográficos
Autores principales: Pennell, Evan Noel, Wagner, Karl-Heinz, Mosawy, Sapha, Bulmer, Andrew Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586953/
https://www.ncbi.nlm.nih.gov/pubmed/31226648
http://dx.doi.org/10.1016/j.redox.2019.101250