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Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation
BACKGROUND: Bilirubin, a by-product of haem catabolism, possesses potent endogenous antioxidant and platelet inhibitory properties. These properties may be useful in inhibiting inappropriate platelet activation and ROS production; for example, during storage for transfusion. Given the hydrophobicity...
Autores principales: | Pennell, Evan Noel, Wagner, Karl-Heinz, Mosawy, Sapha, Bulmer, Andrew Cameron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586953/ https://www.ncbi.nlm.nih.gov/pubmed/31226648 http://dx.doi.org/10.1016/j.redox.2019.101250 |
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