A Splice Site Variant of CDK12 and Breast Cancer in Three Eurasian Populations

CDK12 is a member of the cyclin-dependent kinase family that acts as regulator of DNA damage response gene expression. A c.1047-2A>G splice site variant of the CDK12 gene was recently reported to strongly associate with hereditary breast and ovarian cancer in patients of Tatar ethnic origin. To g...

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Detalles Bibliográficos
Autores principales: Bogdanova, Natalia V., Schürmann, Peter, Valova, Yana, Dubrowinskaja, Natalia, Turmanov, Nurzhan, Yugay, Tatyana, Essimsiitova, Zura, Mingazheva, Elvira, Prokofyeva, Darya, Bermisheva, Marina, Khusnutdinova, Elza, Dörk, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587039/
https://www.ncbi.nlm.nih.gov/pubmed/31259151
http://dx.doi.org/10.3389/fonc.2019.00493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587039/
https://www.ncbi.nlm.nih.gov/pubmed/31259151
http://dx.doi.org/10.3389/fonc.2019.00493

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