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Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle

Immobilization of the lower limbs promotes a catabolic state that reduces muscle mass, whereas physical training promotes an anabolic state that increases muscle mass. Understanding the molecular mechanisms underlying this is of clinical interest, as loss of muscle mass is a major complication to cr...

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Detalles Bibliográficos
Autores principales: Møller, Andreas Buch, Vendelbo, Mikkel Holm, Schjerling, Peter, Couppé, Christian, Møller, Niels, Kjær, Michael, Hansen, Mette, Jessen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587099/
https://www.ncbi.nlm.nih.gov/pubmed/31258486
http://dx.doi.org/10.3389/fphys.2019.00736