Expression of a constitutively active human STING mutant in hematopoietic cells produces an Ifnar1-dependent vasculopathy in mice

STING-associated vasculopathy with onset in infancy (SAVI) is an autoinflammatory disorder characterized by blood vessel occlusions, acral necrosis, myositis, rashes, and pulmonary inflammation that are the result of activating mutations in the STimulator of Interferon Genes (STING). We generated a...

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Detalles Bibliográficos
Autores principales: Martin, Gary R, Henare, Kimiora, Salazar, Carolina, Scheidl-Yee, Teresa, Eggen, Laura J, Tailor, Pankaj P, Kim, Jung Hwan, Podstawka, John, Fritzler, Marvin J, Kelly, Margaret M, Yipp, Bryan G, Jirik, Frank R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587127/
https://www.ncbi.nlm.nih.gov/pubmed/31221625
http://dx.doi.org/10.26508/lsa.201800215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587127/
https://www.ncbi.nlm.nih.gov/pubmed/31221625
http://dx.doi.org/10.26508/lsa.201800215

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