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Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

BACKGROUND: Coronary artery disease (CAD) represents one of the leading causes of morbidity and mortality worldwide. Given the healthcare risks and societal impacts associated with CAD, their clinical management would benefit from improved prevention and prediction tools. Polygenic risk scores (PRS)...

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Detalles Bibliográficos
Autores principales: Wünnemann, Florian, Sin Lo, Ken, Langford-Avelar, Alexandra, Busseuil, David, Dubé, Marie-Pierre, Tardif, Jean-Claude, Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587223/
https://www.ncbi.nlm.nih.gov/pubmed/31184202
http://dx.doi.org/10.1161/CIRCGEN.119.002481