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Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians
BACKGROUND: Coronary artery disease (CAD) represents one of the leading causes of morbidity and mortality worldwide. Given the healthcare risks and societal impacts associated with CAD, their clinical management would benefit from improved prevention and prediction tools. Polygenic risk scores (PRS)...
Autores principales: | Wünnemann, Florian, Sin Lo, Ken, Langford-Avelar, Alexandra, Busseuil, David, Dubé, Marie-Pierre, Tardif, Jean-Claude, Lettre, Guillaume |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587223/ https://www.ncbi.nlm.nih.gov/pubmed/31184202 http://dx.doi.org/10.1161/CIRCGEN.119.002481 |
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