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Target selection for CAR-T therapy

Chimeric antigen receptor-modified T (CAR-T) cells have achieved significant success in the treatment of several hematological malignancies. However, the translation of the existing achievements into the treatment of other tumors, especially solid tumors, is not smooth. In addition to the optimizati...

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Detalles Bibliográficos
Autores principales: Wei, Jianshu, Han, Xiao, Bo, Jian, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587237/
https://www.ncbi.nlm.nih.gov/pubmed/31221182
http://dx.doi.org/10.1186/s13045-019-0758-x