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Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration

Background and aims: Biological mechanisms that control liver regeneration remain poorly defined. However, these mechanisms are remarkable issues in the clinic that affect management of hepatic loss caused by liver surgery, traumatic injury, chronic infection, or liver poisoning. Increasing evidence...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Cheng, Xiawei, Chen, Juntao, Wang, Yao, Wu, Xiaoying, Tian, Rui, Liu, Baoqing, Ding, Xianfeng, Sun, Qiming, Gong, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587347/
https://www.ncbi.nlm.nih.gov/pubmed/31281517
http://dx.doi.org/10.7150/thno.33370