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Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome

Deficiency in homologous recombination repair (HRR) is frequently associated with hormone-responsive cancers, especially the epithelial ovarian cancer (EOC) which shows defects of HRR in up to half of cases. However, whether there are molecular connections between estrogen signaling and HRR deficien...

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Detalles Bibliográficos
Autores principales: Hao, Dapeng, Li, Jingjing, Wang, Jianlin, Meng, Yuan, Zhao, Zhiqiang, Zhang, Chao, Miao, Kai, Deng, Chuxia, Tsang, Benjamin K., Wang, Li, Di, Li-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587348/
https://www.ncbi.nlm.nih.gov/pubmed/31281524
http://dx.doi.org/10.7150/thno.30814