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The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA
N(6)-Methyladenosine (m(6)A) is the most prevalent internal modification in mammalian mRNAs. Although m(6)A is important in many biological processes, its roles in the placenta are unclear. Methods: Levels of global mRNA m(6)A methylation and ALKBH5 expression in recurrent miscarriage (RM) patients...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587351/ https://www.ncbi.nlm.nih.gov/pubmed/31281518 http://dx.doi.org/10.7150/thno.31868 |