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Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions

Intracellular deposits of pathological tau are the hallmark of a broad spectrum of neurodegenerative disorders collectively known as tauopathies, with Alzheimer's disease, a secondary tauopathy, being further characterized by extracellular amyloid plaques. A major obstacle in developing effecti...

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Detalles Bibliográficos
Autores principales: Pandit, Rucha, Leinenga, Gerhard, Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587352/
https://www.ncbi.nlm.nih.gov/pubmed/31281511
http://dx.doi.org/10.7150/thno.34388