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Resolving the Insertion Sites of Polymorphic Duplications Reveals a HERC2 Haplotype under Selection

Polymorphic duplications in humans have been shown to contribute to phenotypic diversity. However, the evolutionary forces that maintain variable duplications across the human genome are largely unexplored. We developed a linkage-disequilibrium based method to detect insertion sites of polymorphic d...

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Detalles Bibliográficos
Autores principales: Saitou, Marie, Gokcumen, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587411/
https://www.ncbi.nlm.nih.gov/pubmed/31124564
http://dx.doi.org/10.1093/gbe/evz107