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Resolving the Insertion Sites of Polymorphic Duplications Reveals a HERC2 Haplotype under Selection
Polymorphic duplications in humans have been shown to contribute to phenotypic diversity. However, the evolutionary forces that maintain variable duplications across the human genome are largely unexplored. We developed a linkage-disequilibrium based method to detect insertion sites of polymorphic d...
Autores principales: | Saitou, Marie, Gokcumen, Omer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587411/ https://www.ncbi.nlm.nih.gov/pubmed/31124564 http://dx.doi.org/10.1093/gbe/evz107 |
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