Allele balance bias identifies systematic genotyping errors and false disease associations

In recent years, next‐generation sequencing (NGS) has become a cornerstone of clinical genetics and diagnostics. Many clinical applications require high precision, especially if rare events such as somatic mutations in cancer or genetic variants causing rare diseases need to be identified. Although...

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Detalles Bibliográficos
Autores principales: Muyas, Francesc, Bosio, Mattia, Puig, Anna, Susak, Hana, Domènech, Laura, Escaramis, Georgia, Zapata, Luis, Demidov, German, Estivill, Xavier, Rabionet, Raquel, Ossowski, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587442/
https://www.ncbi.nlm.nih.gov/pubmed/30353964
http://dx.doi.org/10.1002/humu.23674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587442/
https://www.ncbi.nlm.nih.gov/pubmed/30353964
http://dx.doi.org/10.1002/humu.23674

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