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Exploring Rigid and Flexible Core Trivalent Sialosides for Influenza Virus Inhibition

Herein, the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers interacting with spike proteins of influenza A virus (IAV) X31 is described. Although the flexible Tris‐based trivalent sialosides achieved...

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Detalles Bibliográficos
Autores principales: Kiran, Pallavi, Bhatia, Sumati, Lauster, Daniel, Aleksić, Stevan, Fleck, Carsten, Peric, Natalija, Maison, Wolfgang, Liese, Susanne, Keller, Bettina G., Herrmann, Andreas, Haag, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587447/
https://www.ncbi.nlm.nih.gov/pubmed/30295350
http://dx.doi.org/10.1002/chem.201804826