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Empagliflozin reduces myocardial ketone utilization while preserving glucose utilization in diabetic hypertensive heart disease: A hyperpolarized (13)C magnetic resonance spectroscopy study

AIM: To investigate the effects of the sodium‐glucose co‐transporter‐2 inhibitor empagliflozin on myocardial ketone body utilization in diabetic, obese rats with spontaneously hypertensive heart failure (SHHF), after 6 months of treatment. MATERIALS AND METHODS: Myocardial ketone body utilization wa...

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Detalles Bibliográficos
Autores principales: Abdurrachim, Desiree, Teo, Xing Qi, Woo, Chern Chiuh, Chan, Wei Xin, Lalic, Janise, Lam, Carolyn S. P., Lee, Philip Teck Hock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587455/
https://www.ncbi.nlm.nih.gov/pubmed/30225964
http://dx.doi.org/10.1111/dom.13536