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Increased dynamin expression precedes proteinuria in glomerular disease

Dynamin plays an essential role in maintaining the structure and function of the glomerular filtration barrier. Specifically, dynamin regulates the actin cytoskeleton and the turnover of nephrin in podocytes, and knocking down dynamin expression causes proteinuria. Moreover, promoting dynamin oligom...

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Detalles Bibliográficos
Autores principales: Khalil, Ramzi, Koop, Klaas, Kreutz, Reinhold, Spaink, Herman P, Hogendoorn, Pancras CW, Bruijn, Jan A, Baelde, Hans J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587474/
https://www.ncbi.nlm.nih.gov/pubmed/30350425
http://dx.doi.org/10.1002/path.5181