Cargando…

Increased dynamin expression precedes proteinuria in glomerular disease

Dynamin plays an essential role in maintaining the structure and function of the glomerular filtration barrier. Specifically, dynamin regulates the actin cytoskeleton and the turnover of nephrin in podocytes, and knocking down dynamin expression causes proteinuria. Moreover, promoting dynamin oligom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khalil, Ramzi, Koop, Klaas, Kreutz, Reinhold, Spaink, Herman P, Hogendoorn, Pancras CW, Bruijn, Jan A, Baelde, Hans J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2018
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587474/ https://www.ncbi.nlm.nih.gov/pubmed/30350425 http://dx.doi.org/10.1002/path.5181

Ejemplares similares

Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier
por: Khalil, Ramzi, et al.
Publicado: (2022)

Paratesticular desmoplastic small round cell tumour: an unusual tumour with an unusual fusion; cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH
por: Cliteur, Vincent PM, et al.
Publicado: (2012)

Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes
por: He, Junling, et al.
Publicado: (2020)

Roles of glomerular endothelial hyaluronan in the development of proteinuria
por: Asai, Akimasa, et al.
Publicado: (2021)

Non‐ossifying fibroma: A RAS‐MAPK driven benign bone neoplasm
por: Bovée, Judith VMG, et al.
Publicado: (2019)

Glomerular developmental delay and proteinuria in the preterm neonatal rabbit
por: de Winter, Derek, et al.
Publicado: (2020)

Multiple Osteochondromas: Clinicopathological and Genetic Spectrum and Suggestions for Clinical Management
por: Hameetman, Liesbeth, et al.
Publicado: (2004)

Determination of the optimal target level of proteinuria in the management of patients with glomerular diseases by using different definitions of proteinuria
por: Kee, Youn Kyung, et al.
Publicado: (2017)

Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and Casein Kinase II inhibition as a potential treatment option
por: Willems, Stefan M, et al.
Publicado: (2010)

Insulin Prevents Hyperfiltration and Proteinuria but Not Glomerular Hypertrophy and Increases Mesangial Matrix Expansion in Diabetic Rats
por: Malatiali, Slava, et al.
Publicado: (2017)

Proteinuria and glomerular injury associated with the anti-angiogenesis drug Vargatef™
por: Manjunath, Veena, et al.
Publicado: (2011)

Case of Proteinuria, Worsening Hypertension, and Glomerular Endotheliosis With Erlotinib and Gefitinib
por: Latcha, Sheron, et al.
Publicado: (2018)

The clinical use of biomarkers as prognostic factors in Ewing sarcoma
por: van Maldegem, Annmeik M, et al.
Publicado: (2012)

Long-Term Follow-Up of Proteinuria and Estimated Glomerular Filtration Rate in HIV-Infected Patients with Tubular Proteinuria
por: Peyriere, Hélène, et al.
Publicado: (2015)

Proximal Tubular Hypertrophy and Enlarged Glomerular and Proximal Tubular Urinary Space in Obese Subjects with Proteinuria
por: Tobar, Ana, et al.
Publicado: (2013)

Vegfa Protects the Glomerular Microvasculature in Diabetes
por: Sivaskandarajah, Gavasker A., et al.
Publicado: (2012)

Cystatin C as a surrogate for glomerular filtration rate in the presence of proteinuria
por: Ledson, Thomas, et al.
Publicado: (2008)

Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria
por: Nishad, Rajkishor, et al.
Publicado: (2021)

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction
por: Elmonem, Mohamed A., et al.
Publicado: (2017)

Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment
por: van Maldegem, Annemiek M, et al.
Publicado: (2012)

Overexpression of Myo1e promotes albumin endocytosis by mouse glomerular podocytes mediated by Dynamin
por: Shen, Huijun, et al.
Publicado: (2020)

Phenol levels during intralesional curettage and local adjuvant treatment of benign and low-grade malignant bone tumours
por: Verdegaal, Suzan HM, et al.
Publicado: (2012)

Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo
por: Meijer, Danielle, et al.
Publicado: (2011)

Acute nephrotic-range glomerular proteinuria following ibuprofen intoxication in two cats
por: Herrero, Yaiza, et al.
Publicado: (2022)

The role of a low glomerular density and being overweight in the etiology of proteinuria in CKD patients without known glomerular diseases
por: Okamoto, Hidekazu, et al.
Publicado: (2014)

BCRP expression in schwannoma, plexiform neurofibroma and MPNST
por: de Vries, Maurits, et al.
Publicado: (2017)

The adapter protein Myd88 plays an important role in limiting mycobacterial growth in a zebrafish model for tuberculosis
por: Hosseini, Rohola, et al.
Publicado: (2021)

Erratum to: The role of a low glomerular density and being overweight in the etiology of proteinuria in CKD patients without known glomerular diseases
por: Okamoto, Hidekazu, et al.
Publicado: (2014)

Proteolytic enzyme treatment reduces glomerular immune deposits and proteinuria in passive Heymann nephritis
Publicado: (1986)

The significance of tubular and glomerular proteinuria in critically ill patients with severe acute kidney injury
por: Lim, Christopher Thiam Seong, et al.
Publicado: (2014)

MC1R is dispensable for the proteinuria reducing and glomerular protective effect of melanocortin therapy
por: Qiao, Yingjin, et al.
Publicado: (2016)

Crystalline podocytopathy and tubulopathy without overt glomerular proteinuria in a patient with multiple myeloma
por: Lee, Eun Jeong, et al.
Publicado: (2016)

Effects of Therapy on Urine Neutrophil Gelatinase-Associated Lipocalin in Nondiabetic Glomerular Diseases with Proteinuria
por: Sirisopha, Amnuay, et al.
Publicado: (2016)

Spontaneous abortion as differential diagnosis of intermittent glomerular proteinuria in inactive systemic lupus erythematosus
por: Ullrich, Fabian T. H., et al.
Publicado: (2023)

Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 Multiple Osteochondromas families
por: Jennes, Ivy, et al.
Publicado: (2011)

MIF Increases sFLT1 Expression in Early Uncomplicated Pregnancy and Preeclampsia
por: Yong, Qing, et al.
Publicado: (2023)

Correlation between glomerular filtration rate and urinary N acetyl-beta-D glucosaminidase in children with persistent proteinuria in chronic glomerular disease
por: Hong, Jeong Deok, et al.
Publicado: (2012)

Glomerular Endothelial Cell Injury and Damage Precedes That of Podocytes in Adriamycin-Induced Nephropathy
por: Sun, Yu Bo Yang, et al.
Publicado: (2013)

Intrauterine growth restriction is associated with persistent aortic wall thickening and glomerular proteinuria during infancy
por: Zanardo, Vincenzo, et al.
Publicado: (2011)

The Accumulation of VEGFA in the Glomerular Basement Membrane and Its Relationship with Podocyte Injury and Proteinuria in Alport Syndrome
por: Wang, Haiyan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v0lsrtqs78lcji9fv94ne2l4vd