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Aneuploidy: Cancer strength or vulnerability?

Aneuploidy is a very rare and tissue‐specific event in normal conditions, occurring in a low number of brain and liver cells. Its frequency increases in age‐related disorders and is one of the hallmarks of cancer. Aneuploidy has been associated with defects in the spindle assembly checkpoint (SAC)....

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Detalles Bibliográficos
Autores principales: Simonetti, Giorgia, Bruno, Samantha, Padella, Antonella, Tenti, Elena, Martinelli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587540/
https://www.ncbi.nlm.nih.gov/pubmed/29981145
http://dx.doi.org/10.1002/ijc.31718