Effects of stably incorporated iron on protein phosphatase‐1 structure and activity

Protein phosphatase‐1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes to counteract multiple kinases in signaling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains iron naturally. Iron has been suggested to have an in...

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Detalles Bibliográficos
Autores principales: Salvi, Francesca, Trebacz, Malgorzata, Kokot, Thomas, Hoermann, Bernhard, Rios, Pablo, Barabas, Orsolya, Kӧhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587554/
https://www.ncbi.nlm.nih.gov/pubmed/30403291
http://dx.doi.org/10.1002/1873-3468.13284