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Effects of stably incorporated iron on protein phosphatase‐1 structure and activity
Protein phosphatase‐1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes to counteract multiple kinases in signaling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains iron naturally. Iron has been suggested to have an in...
Autores principales: | Salvi, Francesca, Trebacz, Malgorzata, Kokot, Thomas, Hoermann, Bernhard, Rios, Pablo, Barabas, Orsolya, Kӧhn, Maja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587554/ https://www.ncbi.nlm.nih.gov/pubmed/30403291 http://dx.doi.org/10.1002/1873-3468.13284 |
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