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Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in aortic dissection

BACKGROUND: Aortic dissection (AD) is one of the most lethal cardiovascular diseases. The aim of this study was to identify core genes and pathways revealing pathogenesis in AD. METHODS: We screened differentially expressed mRNAs and miRNAs using mRNA and miRNA expression profile data of AD from Gen...

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Detalles Bibliográficos
Autores principales: Su, Yiming, Li, Qiyi, Zheng, Zhiyong, Wei, Xiaomin, Hou, Peiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587623/
https://www.ncbi.nlm.nih.gov/pubmed/31192949
http://dx.doi.org/10.1097/MD.0000000000016013