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Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring

Maternal immune transfer is the most significant source of protection from early-life infection, but whether maternal transfer of immunity by nursing permanently alters offspring immunity is poorly understood. Here, we identify maternal immune imprinting of offspring nursed by mothers who had a pre-...

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Detalles Bibliográficos
Autores principales: Darby, Matthew G., Chetty, Alisha, Mrjden, Dunja, Rolot, Marion, Smith, Katherine, Mackowiak, Claire, Sedda, Delphine, Nyangahu, Donald, Jaspan, Heather, Toellner, Kai-Michael, Waisman, Ari, Quesniaux, Valerie, Ryffel, Bernhard, Cunningham, Adam F., Dewals, Benjamin G., Brombacher, Frank, Horsnell, William G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587632/
https://www.ncbi.nlm.nih.gov/pubmed/31236458
http://dx.doi.org/10.1126/sciadv.aav3058