Rifampicin Alters Metformin Plasma Exposure but Not Blood Glucose Levels in Diabetic Tuberculosis Patients

The pharmacokinetic (PK) and clinical implications of combining metformin with rifampicin are relevant to increasing numbers of patients with diabetic tuberculosis (TB) across the world and are yet unclear. We assessed the impact of rifampicin on metformin PKs and its glucose‐lowering effect in pati...

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Detalles Bibliográficos
Autores principales: te Brake, Lindsey H.M., Yunivita, Vycke, Livia, Resvi, Soetedjo, Nanny, van Ewijk‐Beneken Kolmer, Eleonora, Koenderink, Jan B., Burger, David M., Santoso, Prayudi, van Crevel, Reinout, Alisjahbana, Bachti, Aarnoutse, Rob E., Ruslami, Rovina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587702/
https://www.ncbi.nlm.nih.gov/pubmed/30222857
http://dx.doi.org/10.1002/cpt.1232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587702/
https://www.ncbi.nlm.nih.gov/pubmed/30222857
http://dx.doi.org/10.1002/cpt.1232

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