PCNA and JNK1‐Stat3 pathways respectively promotes and inhibits diabetes‐associated centrosome amplification by targeting at the ROCK1/14‐3‐3σ complex in human colon cancer HCT116 cells

We have recently reported that type 2 diabetes promotes centrosome amplification via enhancing the expression, biding, and centrosome translocation of rho‐associated coiled‐coil containing protein kinase 1 (ROCK1)/14‐3‐3σ complex in HCT116 cells. In the functional proteomic study, we further investi...

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Detalles Bibliográficos
Autores principales: Lu, Yu Cheng, Wang, Pu, Wang, Jie, Ma, Ronald, Lee, Shao Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587713/
https://www.ncbi.nlm.nih.gov/pubmed/30478982
http://dx.doi.org/10.1002/jcp.27813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587713/
https://www.ncbi.nlm.nih.gov/pubmed/30478982
http://dx.doi.org/10.1002/jcp.27813

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