A novel fusion gene PLEKHA6‐NTRK3 in langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is the most common histiocytosis with constitutive activation of the RAS–RAF–MEK–ERK (MAPKinase) cell signaling pathway. We analyzed 89 cases of BRAF and MAP2K1 mutations by Sanger sequencing, of which 18 cases showed that these two gene mutations are negative. Wh...

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Detalles Bibliográficos
Autores principales: Cai, Jiaoyang, Huang, Xia, Yin, Minzhi, Pan, Ci, Song, Lili, Zhan, Zhiyan, Chen, Jing, Gao, Yijin, Tang, Jingyan, Li, Yanxin, Shen, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Molecular Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587734/
https://www.ncbi.nlm.nih.gov/pubmed/30098202
http://dx.doi.org/10.1002/ijc.31636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587734/
https://www.ncbi.nlm.nih.gov/pubmed/30098202
http://dx.doi.org/10.1002/ijc.31636

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