Hunting for the high‐affinity state of G‐protein‐coupled receptors with agonist tracers: Theoretical and practical considerations for positron emission tomography imaging

The concept of the high‐affinity state postulates that a certain subset of G‐protein‐coupled receptors is primarily responsible for receptor signaling in the living brain. Assessing the abundance of this subset is thus potentially highly relevant for studies concerning the responses of neurotransmis...

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Detalles Bibliográficos
Autores principales: Shalgunov, Vladimir, van Waarde, Aren, Booij, Jan, Michel, Martin C., Dierckx, Rudi A. J. O., Elsinga, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587759/
https://www.ncbi.nlm.nih.gov/pubmed/30450619
http://dx.doi.org/10.1002/med.21552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587759/
https://www.ncbi.nlm.nih.gov/pubmed/30450619
http://dx.doi.org/10.1002/med.21552

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