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Dose‐ and time‐dependent alterations in lipid metabolism after pharmacological PGC‐1α activation in L6 myotubes

Pyrroloquinoline quinone (PQQ) acts as a powerful modulator of PGC‐1α activation and therefore regulates multiple pathways involved in cellular energy homeostasis. In the present study, we assessed the effects of L6 myotubes incubation with 0.5, 1, and 3 μM PQQ solution for 2 and 24 hr with respect...

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Detalles Bibliográficos
Autores principales: Supruniuk, Elżbieta, Mikłosz, Agnieszka, Chabowski, Adrian, Łukaszuk, Bartłomiej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587770/
https://www.ncbi.nlm.nih.gov/pubmed/30523639
http://dx.doi.org/10.1002/jcp.27872