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Prevention of allergy by virus‐like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model

BACKGROUND: In high‐risk populations, allergen‐specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the...

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Detalles Bibliográficos
Autores principales: Kratzer, Bernhard, Köhler, Cordula, Hofer, Sandra, Smole, Ursula, Trapin, Doris, Iturri, Jagoba, Pum, Dietmar, Kienzl, Philip, Elbe‐Bürger, Adelheid, Gattinger, Pia, Mittermann, Irene, Linhart, Birgit, Gadermaier, Gabriele, Jahn‐Schmid, Beatrice, Neunkirchner, Alina, Valenta, Rudolf, Pickl, Winfried F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587790/
https://www.ncbi.nlm.nih.gov/pubmed/30035810
http://dx.doi.org/10.1111/all.13573