Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Bile duct ligation (BDL) is an experimental procedure that mimics obstructive cholestatic disease. One of the early consequences of BDL in rodents is the appearance of so‐called bile infarcts that correspond to Charcot‐Gombault necrosis in human cholestasis. The mechanisms causing bile infarcts and...

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Detalles Bibliográficos
Autores principales: Ghallab, Ahmed, Hofmann, Ute, Sezgin, Selahaddin, Vartak, Nachiket, Hassan, Reham, Zaza, Ayham, Godoy, Patricio, Schneider, Kai Markus, Guenther, Georgia, Ahmed, Yasser A., Abbas, Aya A., Keitel, Verena, Kuepfer, Lars, Dooley, Steven, Lammert, Frank, Trautwein, Christian, Spiteller, Michael, Drasdo, Dirk, Hofmann, Alan F., Jansen, Peter L.M., Hengstler, Jan G., Reif, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587841/
https://www.ncbi.nlm.nih.gov/pubmed/30102412
http://dx.doi.org/10.1002/hep.30213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587841/
https://www.ncbi.nlm.nih.gov/pubmed/30102412
http://dx.doi.org/10.1002/hep.30213

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