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Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7‐mediated chondroitin sulfate proteoglycan production

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS), characterized by inflammation‐mediated demyelination, axonal injury and neurodegeneration. The mechanisms underlying impaired neuronal function are not fully understood, but evidence is accumulating that...

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Detalles Bibliográficos
Autores principales: Kamermans, Alwin, Planting, Kirsten E., Jalink, Kees, van Horssen, Jack, de Vries, Helga E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587975/
https://www.ncbi.nlm.nih.gov/pubmed/30453391
http://dx.doi.org/10.1002/glia.23526