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In Chronic Hepatitis C Infection, Myeloid-Derived Suppressor Cell Accumulation and T Cell Dysfunctions Revert Partially and Late After Successful Direct-Acting Antiviral Treatment

Chronic HCV infection is characterized by several immunological alterations, such as the accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is unclear whether direct-acting antiviral (DAA)-mediated HCV clearance restores immune dysfunctions. We performed a phenotypic c...

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Detalles Bibliográficos
Autores principales: Telatin, Valentina, Nicoli, Francesco, Frasson, Chiara, Menegotto, Nicola, Barbaro, Francesco, Castelli, Eleonora, Erne, Elke, Palù, Giorgio, Caputo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588015/
https://www.ncbi.nlm.nih.gov/pubmed/31259160
http://dx.doi.org/10.3389/fcimb.2019.00190