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Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain

Transgenic Tg2576 mice expressing human amyloid precursor protein (hAPP) with the Swedish mutation are among the most frequently used animal models to study the amyloid pathology related to Alzheimer's disease (AD). The transgene expression in this model is considered to be neuron‐specific. Usi...

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Detalles Bibliográficos
Autores principales: Heiland, Tina, Zeitschel, Ulrike, Puchades, Maja A., Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F., Bjaalie, Jan G., Hartlage‐Rübsamen, Maike, Roßner, Steffen, Höfling, Corinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588085/
https://www.ncbi.nlm.nih.gov/pubmed/30485540
http://dx.doi.org/10.1002/glia.23550