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Metabolic reprogramming dynamics in tumor spheroids: Insights from a multicellular, multiscale model

Mathematical modeling provides the predictive ability to understand the metabolic reprogramming and complex pathways that mediate cancer cells’ proliferation. We present a mathematical model using a multiscale, multicellular approach to simulate avascular tumor growth, applied to pancreatic cancer....

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Detalles Bibliográficos
Autores principales: Roy, Mahua, Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588258/
https://www.ncbi.nlm.nih.gov/pubmed/31185009
http://dx.doi.org/10.1371/journal.pcbi.1007053