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Metabolic reprogramming dynamics in tumor spheroids: Insights from a multicellular, multiscale model
Mathematical modeling provides the predictive ability to understand the metabolic reprogramming and complex pathways that mediate cancer cells’ proliferation. We present a mathematical model using a multiscale, multicellular approach to simulate avascular tumor growth, applied to pancreatic cancer....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588258/ https://www.ncbi.nlm.nih.gov/pubmed/31185009 http://dx.doi.org/10.1371/journal.pcbi.1007053 |