KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

Vascular endothelial growth factor-C (VEGF-C) acts primarily on endothelial cells, but also on non-vascular targets, for example in the CNS and immune system. Here we describe a novel, unique VEGF-C form in the human reproductive system produced via cleavage by kallikrein-related peptidase 3 (KLK3),...

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Detalles Bibliográficos
Autores principales: Jha, Sawan Kumar, Rauniyar, Khushbu, Chronowska, Ewa, Mattonet, Kenny, Maina, Eunice Wairimu, Koistinen, Hannu, Stenman, Ulf-Håkan, Alitalo, Kari, Jeltsch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588350/
https://www.ncbi.nlm.nih.gov/pubmed/31099754
http://dx.doi.org/10.7554/eLife.44478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588350/
https://www.ncbi.nlm.nih.gov/pubmed/31099754
http://dx.doi.org/10.7554/eLife.44478

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