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Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses
Current paradigms of cell intrinsic immunity to RNA viruses center on virus-triggered inducible antiviral responses initiated by RIG-I-like receptors (RLRs) or Toll-like receptors (TLRs) that sense pathogen-associated molecular patterns, and signal downstream through interferon regulatory factors (I...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588457/ https://www.ncbi.nlm.nih.gov/pubmed/30988429 http://dx.doi.org/10.1038/s41564-019-0425-6 |